JPS014
Modify Date: 2025-08-26 11:32:50
JPS014 structure
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Common Name | JPS014 | ||
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| CAS Number | 2669785-76-4 | Molecular Weight | 854.07 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C46H59N7O7S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of JPS014JPS014 is a benzamide-based Von Hippel-Lindau (VHL) E3-ligase proteolysis targeting chimeras (PROTAC). JPS014 degrades class I histone deacetylase (HDAC). JPS014 is potent HDAC1/2 degrader correlated with greater total differentially expressed genes and enhanced apoptosis in HCT116 cells[1]. |
| Name | JPS014 |
|---|
| Description | JPS014 is a benzamide-based Von Hippel-Lindau (VHL) E3-ligase proteolysis targeting chimeras (PROTAC). JPS014 degrades class I histone deacetylase (HDAC). JPS014 is potent HDAC1/2 degrader correlated with greater total differentially expressed genes and enhanced apoptosis in HCT116 cells[1]. |
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| Related Catalog | |
| References |
| Molecular Formula | C46H59N7O7S |
|---|---|
| Molecular Weight | 854.07 |