Cap-dependent endonuclease-IN-10

Modify Date: 2025-08-24 22:28:03

Cap-dependent endonuclease-IN-10 Structure
Cap-dependent endonuclease-IN-10 structure
Common Name Cap-dependent endonuclease-IN-10
CAS Number 2663989-04-4 Molecular Weight 524.50
Density N/A Boiling Point N/A
Molecular Formula C25H18F2N4O5S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Cap-dependent endonuclease-IN-10


Cap-dependent endonuclease-IN-10 is a potent inhibitor of cap-dependent endonuclease (CEN). Not only can Cap-dependent endonuclease-IN-10 inhibit influenza virus well, but also has lower cytotoxicity, better in vivo pharmacokinetic and in vivo pharmacodynamic properties, and better hepatic microsomal stability. Cap-dependent endonuclease-IN-10 has the potential for the research of viral infections (including influenza A, influenza B and influenza C) (extracted from patent WO2021129799A1, compound 1-1)[1].

 Names

Name Cap-dependent endonuclease-IN-10

 Cap-dependent endonuclease-IN-10 Biological Activity

Description Cap-dependent endonuclease-IN-10 is a potent inhibitor of cap-dependent endonuclease (CEN). Not only can Cap-dependent endonuclease-IN-10 inhibit influenza virus well, but also has lower cytotoxicity, better in vivo pharmacokinetic and in vivo pharmacodynamic properties, and better hepatic microsomal stability. Cap-dependent endonuclease-IN-10 has the potential for the research of viral infections (including influenza A, influenza B and influenza C) (extracted from patent WO2021129799A1, compound 1-1)[1].
Related Catalog
References

[1]. Yingjun Zhang, et al. Influenza virus replication inhibitors and their uses. Patent WO2021129799A1.

 Chemical & Physical Properties

Molecular Formula C25H18F2N4O5S
Molecular Weight 524.50
InChIKey FOQDXMRBJYEATR-QUCCMNQESA-N
SMILES O=C1c2c(O)c(=O)ccn2N(C2c3ccc(F)c(F)c3Cn3c(=O)sc4cccc2c43)C2COCCN12
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