Cap-dependent endonuclease-IN-10

Cap-dependent endonuclease-IN-10 is a potent inhibitor of cap-dependent endonuclease (CEN). Not only can Cap-dependent endonuclease-IN-10 inhibit influenza virus well, but also has lower cytotoxicity, better in vivo pharmacokinetic and in vivo pharmacodynamic properties, and better hepatic microsomal stability. Cap-dependent endonuclease-IN-10 has the potential for the research of viral infections (including influenza A, influenza B and influenza C) (extracted from patent WO2021129799A1, compound 1-1)[1].

Signaling Pathways >> Anti-infection >> Influenza Virus

Research Areas >> Infection

[1]. Yingjun Zhang, et al. Influenza virus replication inhibitors and their uses. Patent WO2021129799A1.