Endovion

Modify Date: 2025-08-25 16:59:54

Endovion structure	Common Name	Endovion
	CAS Number	265646-85-3	Molecular Weight	495.18
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₆H₉BrF₆N₆O	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Endovion

Endovion (NS3728) is a pharmacological anion channel inhibitor (like chloride channel) and the specific VRAC/VSOAC blocker. Endovion (NS3728) is also an Anoctamin-1 (ANO 1) channel inhibitor[1][2].

Name	1-[3,5-bis(trifluoromethyl)phenyl]-3-[5-bromo-2-(2H-tetrazol-5-yl)phenyl]urea
Synonym	More Synonyms

Description	Endovion (NS3728) is a pharmacological anion channel inhibitor (like chloride channel) and the specific VRAC/VSOAC blocker. Endovion (NS3728) is also an Anoctamin-1 (ANO 1) channel inhibitor[1][2].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> Chloride Channel Research Areas >> Others
Target	Chloride channel, VRAC/VSOAC[1]. ANO1[2].
References	[1]. Sørensen BH, et al. Downregulation of LRRC8A protects human ovarian and alveolar carcinoma cells against Cisplatin-induced expression of p53, MDM2, p21Waf1/Cip1, and Caspase-9/-3 activation. Am J Physiol Cell Physiol. 2016 Jun 1;310(11):C857-73. [2]. Sauter DR, et al. ANO1 (TMEM16A) in pancreatic ductal adenocarcinoma (PDAC). Pflugers Arch. 2015 Jul;467(7):1495-1508.

Molecular Formula	C₁₆H₉BrF₆N₆O
Molecular Weight	495.18
Exact Mass	493.99300
PSA	99.08000
LogP	5.39740
Storage condition	2-8℃

Urea,N-(3,5-bis(trifluoromethyl)phenyl)-N'-(4-bromo-2-(1H-tetrazol-5-yl)phenyl)

UNII-943YH53W21

NS 3728

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Endovion
Price: Check
Purity: 99.0%
Delivery: 10 Day
Contact: Yang
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DC Chemicals Limited
China
Product Name: Endovion (NS 3728)
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

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Price: ￥990/5 mg

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Endovion

Use of Endovion

Names

Endovion Biological Activity

Chemical & Physical Properties

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.