2'-O-Methylcytidine-d3

Modify Date: 2024-02-05 00:14:29

2'-O-Methylcytidine-d3 Structure
2'-O-Methylcytidine-d3 structure
Common Name 2'-O-Methylcytidine-d3
CAS Number 2653209-08-4 Molecular Weight 260.26
Density N/A Boiling Point N/A
Molecular Formula C10H12D3N3O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 2'-O-Methylcytidine-d3


2'-O-Methylcytidine-d3 is deuterium labeled 2'-O-Methylcytidine (HY-W011834). 2'-O-Methylcytidine is a 2'-substituted nucleoside as a inhibitor of HCV replication. 2'-O-Methylcytidine inhibits RNA-dependent RNA polymerase (NS5B)-catalyzed RNA synthesis in vitro, in a manner that is competitive with substrate nucleoside triphosphate.

 Names

Name 2'-O-Methylcytidine-d3

 2'-O-Methylcytidine-d3 Biological Activity

Description 2'-O-Methylcytidine-d3 is deuterium labeled 2'-O-Methylcytidine (HY-W011834). 2'-O-Methylcytidine is a 2'-substituted nucleoside as a inhibitor of HCV replication. 2'-O-Methylcytidine inhibits RNA-dependent RNA polymerase (NS5B)-catalyzed RNA synthesis in vitro, in a manner that is competitive with substrate nucleoside triphosphate.
Related Catalog
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Steven S Carroll, et al. Inhibition of hepatitis C virus RNA replication by 2'-modified nucleoside analogs. J Biol Chem. 2003 Apr 4;278(14):11979-84  

 Chemical & Physical Properties

Molecular Formula C10H12D3N3O5
Molecular Weight 260.26
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