2653209-08-4

2653209-08-4 structure

Name: 2'-O-Methylcytidine-d3
Chemical Name: 2'-O-Methylcytidine-d3
CAS Number: 2653209-08-4
Molecular Formula: C₁₀H₁₂D₃N₃O₅
Molecular Weight: 260.26
Catalog: Signaling Pathways Anti-infection HCV
Create Date: 2024-02-05 00:14:29
Modify Date: 2024-02-05 00:14:29
2'-O-Methylcytidine-d3 is deuterium labeled 2'-O-Methylcytidine (HY-W011834). 2'-O-Methylcytidine is a 2'-substituted nucleoside as a inhibitor of HCV replication. 2'-O-Methylcytidine inhibits RNA-dependent RNA polymerase (NS5B)-catalyzed RNA synthesis in vitro, in a manner that is competitive with substrate nucleoside triphosphate.

Name	2'-O-Methylcytidine-d3

Description	2'-O-Methylcytidine-d3 is deuterium labeled 2'-O-Methylcytidine (HY-W011834). 2'-O-Methylcytidine is a 2'-substituted nucleoside as a inhibitor of HCV replication. 2'-O-Methylcytidine inhibits RNA-dependent RNA polymerase (NS5B)-catalyzed RNA synthesis in vitro, in a manner that is competitive with substrate nucleoside triphosphate.
Related Catalog	Signaling Pathways >> Anti-infection >> HCV Research Areas >> Infection
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Steven S Carroll, et al. Inhibition of hepatitis C virus RNA replication by 2'-modified nucleoside analogs. J Biol Chem. 2003 Apr 4;278(14):11979-84

Molecular Formula	C₁₀H₁₂D₃N₃O₅
Molecular Weight	260.26