KRAS G12C inhibitor 28

Modify Date: 2025-08-30 11:22:37

KRAS G12C inhibitor 28 Structure
KRAS G12C inhibitor 28 structure
Common Name KRAS G12C inhibitor 28
CAS Number 2649004-88-4 Molecular Weight 635.64
Density N/A Boiling Point N/A
Molecular Formula C33H36F2N5O4P Melting Point N/A
MSDS N/A Flash Point N/A

 Use of KRAS G12C inhibitor 28


KRAS G12C inhibitor 28 is a KRAS G12C inhibitor with an IC50 of 57 nM. KRAS G12C inhibitor 28 has antitumor effects (WO2021113595A1; Example 1)[1].

 Names

Name KRAS G12C inhibitor 28

 KRAS G12C inhibitor 28 Biological Activity

Description KRAS G12C inhibitor 28 is a KRAS G12C inhibitor with an IC50 of 57 nM. KRAS G12C inhibitor 28 has antitumor effects (WO2021113595A1; Example 1)[1].
Related Catalog
Target

KRas G12C:57 nM (IC50)

References

[1]. Don Zhang, et al. Phosphorus derivatives as kras inhibitors. WO2021113595A1.

 Chemical & Physical Properties

Molecular Formula C33H36F2N5O4P
Molecular Weight 635.64
InChIKey AULVAQHFJPQQED-FQEVSTJZSA-N
SMILES C=CC(=O)N1CCN(c2nc(=O)n(-c3c(C)cc(P(C)(C)=O)cc3C(C)C)c3nc(-c4c(O)cccc4F)c(F)cc23)C(C)C1
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