KRAS G12C inhibitor 28 structure
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Common Name | KRAS G12C inhibitor 28 | ||
|---|---|---|---|---|
| CAS Number | 2649004-88-4 | Molecular Weight | 635.64 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C33H36F2N5O4P | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of KRAS G12C inhibitor 28KRAS G12C inhibitor 28 is a KRAS G12C inhibitor with an IC50 of 57 nM. KRAS G12C inhibitor 28 has antitumor effects (WO2021113595A1; Example 1)[1]. |
| Name | KRAS G12C inhibitor 28 |
|---|
| Description | KRAS G12C inhibitor 28 is a KRAS G12C inhibitor with an IC50 of 57 nM. KRAS G12C inhibitor 28 has antitumor effects (WO2021113595A1; Example 1)[1]. |
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| Related Catalog | |
| Target |
KRas G12C:57 nM (IC50) |
| References |
[1]. Don Zhang, et al. Phosphorus derivatives as kras inhibitors. WO2021113595A1. |
| Molecular Formula | C33H36F2N5O4P |
|---|---|
| Molecular Weight | 635.64 |
| InChIKey | AULVAQHFJPQQED-FQEVSTJZSA-N |
| SMILES | C=CC(=O)N1CCN(c2nc(=O)n(-c3c(C)cc(P(C)(C)=O)cc3C(C)C)c3nc(-c4c(O)cccc4F)c(F)cc23)C(C)C1 |