2761380-32-7
2761380-32-7 structure
- Name: KRAS G12C inhibitor 49
- Chemical Name: KRAS G12C inhibitor 49
- CAS Number: 2761380-32-7
- Molecular Formula: C31H31ClN6O3
- Molecular Weight: 571.07
- Catalog: Signaling Pathways GPCR/G Protein Ras
- Create Date: 2022-09-10 17:16:42
- Modify Date: 2024-01-13 07:18:46
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KRAS G12C inhibitor 49 (Compound 3-2M) is an orally active KRAS G12C inhibitor. KRAS G12C inhibitor 49 shows antitumor activity[1].
| Name | KRAS G12C inhibitor 49 |
|---|
| Description | KRAS G12C inhibitor 49 (Compound 3-2M) is an orally active KRAS G12C inhibitor. KRAS G12C inhibitor 49 shows antitumor activity[1]. |
|---|---|
| Related Catalog | |
| Target |
KRAS(G12C) |
| In Vitro | KRAS G12C inhibitor 49 (Compound 3-2M) shows antiproliferative activity against MIAPaCa-2 and H358 with IC50 values of both 0-50 nM[1]. |
| References |
[1]. ZHANG Qiang, et al. Aromatic compound and application thereof in antitumor drug. WO2022028346A1. |
| Molecular Formula | C31H31ClN6O3 |
|---|---|
| Molecular Weight | 571.07 |