Pomalidomide-C11-NH2

Modify Date: 2025-10-18 17:08:19

Pomalidomide-C11-NH2 Structure
Pomalidomide-C11-NH2 structure
 Common Name Pomalidomide-C11-NH2
CAS Number 2648285-39-4 Molecular Weight 442.55
Density N/A Boiling Point N/A
Molecular Formula C24H34N4O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Pomalidomide-C11-NH2


Pomalidomide-C11-NH2 is the Pomalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Pomalidomide-C11-NH2 can be connected to the ligand for protein by a linker to form PROTAC[1].

 Names

Name Pomalidomide-C11-NH2

 Pomalidomide-C11-NH2 Biological Activity

Description Pomalidomide-C11-NH2 is the Pomalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Pomalidomide-C11-NH2 can be connected to the ligand for protein by a linker to form PROTAC[1].
Related Catalog
References

[1]. Chotitumnavee J, et al. Selective degradation of histone deacetylase 8 mediated by a proteolysis targeting chimera (PROTAC). Chem Commun (Camb). 2022 Apr 7;58(29):4635-4638.  

 Chemical & Physical Properties

Molecular Formula C24H34N4O4
Molecular Weight 442.55
InChIKey KMSUSGNCESOVGM-UHFFFAOYSA-N
SMILES NCCCCCCCCCCCNc1cccc2c1C(=O)N(C1CCC(=O)NC1=O)C2=O
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