C.I. Solvent Orange 2

Modify Date: 2025-08-24 10:10:59

C.I. Solvent Orange 2 Structure
C.I. Solvent Orange 2 structure
Common Name C.I. Solvent Orange 2
CAS Number 2646-17-5 Molecular Weight 262.30600
Density 1.15 g/cm3 Boiling Point 464.9ºC at 760 mmHg
Molecular Formula C17H14N2O Melting Point 124-126°C
MSDS Chinese USA Flash Point 306.4ºC
Symbol GHS08
GHS08
Signal Word Warning

 Use of C.I. Solvent Orange 2


C.I. Solvent Orange 2 is a dye.

 Names

Name Solvent Orange 2
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.15 g/cm3
Boiling Point 464.9ºC at 760 mmHg
Melting Point 124-126°C
Molecular Formula C17H14N2O
Molecular Weight 262.30600
Flash Point 306.4ºC
Exact Mass 262.11100
PSA 44.95000
LogP 5.26920
Vapour Pressure 3.34E-07mmHg at 25°C
Index of Refraction 1.624

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
QL5425000
CHEMICAL NAME :
2-Naphthol, 1-(o-tolylazo)-
CAS REGISTRY NUMBER :
2646-17-5
BEILSTEIN REFERENCE NO. :
0959684
LAST UPDATED :
199709
DATA ITEMS CITED :
18
MOLECULAR FORMULA :
C17-H14-N2-O
MOLECULAR WEIGHT :
262.33
WISWESSER LINE NOTATION :
L66J BNUNR B1& CQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
5 gm/kg
TOXIC EFFECTS :
Behavioral - food intake (animal) Gastrointestinal - hypermotility, diarrhea Nutritional and Gross Metabolic - weight loss or decreased weight gain
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
200 mg/kg
TOXIC EFFECTS :
Behavioral - food intake (animal) Lungs, Thorax, or Respiration - respiratory stimulation Gastrointestinal - changes in structure or function of salivary glands
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
5 gm/kg
TOXIC EFFECTS :
Behavioral - food intake (animal) Gastrointestinal - hypermotility, diarrhea Nutritional and Gross Metabolic - weight loss or decreased weight gain
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
60 mg/kg
TOXIC EFFECTS :
Behavioral - food intake (animal) Lungs, Thorax, or Respiration - respiratory stimulation Gastrointestinal - changes in structure or function of salivary glands
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
56 gm/kg/20W-I
TOXIC EFFECTS :
Blood - pigmented or nucleated red blood cells Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - changes in testicular weight
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
115 gm/kg/44W-C
TOXIC EFFECTS :
Related to Chronic Data - death
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
6 gm/kg/52W
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria Gastrointestinal - tumors
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Implant
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
50 mg/kg
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Kidney, Ureter, Bladder - tumors

MUTATION DATA

TEST SYSTEM :
Rodent - mouse
DOSE/DURATION :
200 mg/kg/48H (Intermittent)
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 389,3,1997 *** REVIEWS *** IARC Cancer Review:Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 8,165,1975 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 8,165,1975 IARC Cancer Review:Group 2B IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987 TOXICOLOGY REVIEW ARVPAX Annual Review of Pharmacology. (Palo Alto, CA) V.1-15, 1961-75. For publisher information, see ARPTDI. Volume(issue)/page/year: 14,127,1974 TOXICOLOGY REVIEW AEHLAU Archives of Environmental Health. (Heldref Pub., 4000 Albemarle St., NW, Washington, DC 20016) V.1- 1960- Volume(issue)/page/year: 23,6,1971

 Safety Information

Symbol GHS08
GHS08
Signal Word Warning
Hazard Statements H351
Precautionary Statements P281
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn: Harmful;
Risk Phrases R40
Safety Phrases S36
RIDADR NONH for all modes of transport
RTECS QL5425000
HS Code 2928000090

 Customs

HS Code 2928000090
Summary 2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

 Articles5

More Articles
Furoquinoline alkaloids as photosensitizers in Chlamydomonas reinhardtii.

Mutat. Res. 249(1) , 105-10, (1991)

Seven naturally occurring furoquinoline alkaloids were investigated for their photobiological activity using arg-1 cells of Chlamydomonas reinhardtii. UV-A-mediated toxicity of the compounds was calcu...

Effect of 1-m-tolueneazo-2-naphthol on hepatic drug metabolism. I. Induction of cytochrome P-448.

J. Pharmacobiodyn. 5(4) , 259-65, (1982)

Treatment of rats with 1-m-tolueneazo-2-naphthol (mTAN) caused marked increase in liver weight, microsomal 7-ethoxycoumarin O-deethylase activity and cytochrome P-450 content, with 2 nm hypochromic sh...

The effect of tyrosine conjugation on the critical micellar concentration of free and glycine-conjugated bile salts.

Biochim. Biophys. Acta 876(3) , 677-83, (1986)

We investigated the effect of conjugation with the aromatic amino acid tyrosine on the critical micellar concentration (CMC) of bile salts. The CMC values were determined by surface tension and by dye...

 Synonyms

ORANGE OT
Oil Orange SS
1-(o-Tolylazo)-2-naphthol
toluene-<2 azo 1>-2-naphthol
orangess
fatorangeii
Orange RC
oranzss
oilorangeot
MFCD00059523
EINECS 220-162-8
aforangeno2
DAIDAI403
1-(o-Tolylazo)-2-naphthol,Solvent Orange 2
1-[(2-Methylphenyl)Azo]-2-Naphthol
corange2
1-<(2'-toluic)azo>-2-naphthol
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