PAD4-IN-2

Modify Date: 2025-09-19 16:10:01

PAD4-IN-2 Structure
PAD4-IN-2 structure
 Common Name PAD4-IN-2
CAS Number 2642327-52-2 Molecular Weight 503.70
Density N/A Boiling Point N/A
Molecular Formula C20H23BClN7O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PAD4-IN-2


PAD4-IN-2 (compound 5i) is a PAD4 inhibitor (IC50=1.94 μM). PAD4-IN-2 inhibits tumor growth in mice by specifically inhibiting the PAD4-H3cit-NETs pathway in neutrophils[1].

 Names

Name PAD4-IN-2

 PAD4-IN-2 Biological Activity

Description PAD4-IN-2 (compound 5i) is a PAD4 inhibitor (IC50=1.94 μM). PAD4-IN-2 inhibits tumor growth in mice by specifically inhibiting the PAD4-H3cit-NETs pathway in neutrophils[1].
Related Catalog
Target

IC50: 1.94 μM (PAD4)[1].

References

[1]. Zhu D, et al. Highly-tumor-targeted PAD4 inhibitors with PBA modification inhibit tumors in vivo by specifically inhibiting the PAD4-H3cit-NETs pathway in neutrophils. Eur J Med Chem. 2023 Oct 5;258:115619.  

 Chemical & Physical Properties

Molecular Formula C20H23BClN7O6
Molecular Weight 503.70
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Chemsrc provides PAD4-IN-2(CAS#:2642327-52-2) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of PAD4-IN-2 are included as well.>> amp version: PAD4-IN-2

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