Glyceryl monocaprate

Modify Date: 2024-01-08 16:37:18

Glyceryl monocaprate Structure
Glyceryl monocaprate structure
Common Name Glyceryl monocaprate
CAS Number 26402-22-2 Molecular Weight 246.34300
Density 1.017 g/cm3 Boiling Point N/A
Molecular Formula C13H26O4 Melting Point 53ºC
MSDS N/A Flash Point 129.6ºC

 Use of Glyceryl monocaprate


Glyceryl monocaprate (Monolaurin) is a 1-monoglyceride of capric acid against gram-positive bacterial infections[1]. Glyceryl monocaprate (Monolaurin) has inhibitory effect on Herpes Simplex Virus (HSV) and offers an effective treatment for herpes labialiss[2].

 Names

Name monocaprin
Synonym More Synonyms

 Glyceryl monocaprate Biological Activity

Description Glyceryl monocaprate (Monolaurin) is a 1-monoglyceride of capric acid against gram-positive bacterial infections[1]. Glyceryl monocaprate (Monolaurin) has inhibitory effect on Herpes Simplex Virus (HSV) and offers an effective treatment for herpes labialiss[2].
Related Catalog
Target

IC50: Gram-positive Bacterial; HSV[1][2]

In Vitro Glyceryl monocaprate (Monolaurin) has an antimicrobial activity against gram-positive ATCC SA 29123[1].
In Vivo Glyceryl monocaprate (Monolaurin) combines with low-dose doxycycline offers an effective treatment for herpes labialiss, significantly reducing time to healing and pain compared with the placebo and monocaprin alone[2].
References

[1]. Chan WY, et al. In vitro antimicrobial activity of seven adjuvants against common pathogens associated with canine otitis externa.Vet Dermatol. 2019 Apr;30(2):133-e38.

[2]. Skulason S, et al. A study of the clinical activity of a gel combining monocaprin and doxycycline: a novel treatment for herpes labialis.J Oral Pathol Med. 2012 Jan;41(1):61-7.

 Chemical & Physical Properties

Density 1.017 g/cm3
Melting Point 53ºC
Molecular Formula C13H26O4
Molecular Weight 246.34300
Flash Point 129.6ºC
Exact Mass 246.18300
PSA 66.76000
LogP 2.02350
Vapour Pressure 5.96E-07mmHg at 25°C
Index of Refraction 1.466
Storage condition −20°C

 Safety Information

WGK Germany 1

 Synonyms

1-Monodecanoyl Glycerol
EINECS 247-667-6
Glycerol α-Monodecanoate
2,3-Dihydroxypropyl decanoate
MFCD00056656
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