Exarafenib

Modify Date: 2025-08-25 20:04:50

Exarafenib structure	Common Name	Exarafenib
	CAS Number	2639957-39-2	Molecular Weight	521.58
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₆H₃₄F₃N₅O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Exarafenib

Exarafenib (RAF/KIN_2787) is a potent, orally active pan-RAF inhibitor. Exarafenib has anticancer activity by suppression of downstream MAPK pathway signaling. Exarafenib can be used for cancer research[1][2].

Name	Exarafenib

Description	Exarafenib (RAF/KIN_2787) is a potent, orally active pan-RAF inhibitor. Exarafenib has anticancer activity by suppression of downstream MAPK pathway signaling. Exarafenib can be used for cancer research[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> MAPK/ERK Pathway >> p38 MAPK Signaling Pathways >> MAPK/ERK Pathway >> Raf
References	[1]. Miller N, et, al. Antitumor activity of KIN-2787, a next-generation pan-RAF inhibitor, in combination with MEK inhibition in preclinical models of human NRAS mutant melanoma.2022 Jun 2;40(16): e15099. [2]. WHO Drug Information. International Nonproprietary Names for Pharmaceutical

Description

Related Catalog

Research Areas >> Cancer

Signaling Pathways >> MAPK/ERK Pathway >> p38 MAPK

Signaling Pathways >> MAPK/ERK Pathway >> Raf

References

[1]. Miller N, et, al. Antitumor activity of KIN-2787, a next-generation pan-RAF inhibitor, in combination with MEK inhibition in preclinical models of human NRAS mutant melanoma.2022 Jun 2;40(16): e15099.

[2]. WHO Drug Information. International Nonproprietary Names for Pharmaceutical