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Exarafenib

Names

[ CAS No. ]:
2639957-39-2

[ Name ]:
Exarafenib

Biological Activity

[Description]:

Exarafenib (RAF/KIN_2787) is a potent, orally active pan-RAF inhibitor. Exarafenib has anticancer activity by suppression of downstream MAPK pathway signaling. Exarafenib can be used for cancer research[1][2].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> MAPK/ERK Pathway >> p38 MAPK
Signaling Pathways >> MAPK/ERK Pathway >> Raf

[References]

[1]. Miller N, et, al. Antitumor activity of KIN-2787, a next-generation pan-RAF inhibitor, in combination with MEK inhibition in preclinical models of human NRAS mutant melanoma.2022 Jun 2;40(16): e15099.

[2]. WHO Drug Information. International Nonproprietary Names for Pharmaceutical

Chemical & Physical Properties

[ Molecular Formula ]:
C26H34F3N5O3

[ Molecular Weight ]:
521.58

Related Compounds