p53 Activator 5

Modify Date: 2025-11-02 17:46:46

p53 Activator 5 Structure
p53 Activator 5 structure
Common Name p53 Activator 5
CAS Number 2636840-37-2 Molecular Weight 566.58
Density N/A Boiling Point N/A
Molecular Formula C29H32F6N4O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of p53 Activator 5


p53 Activator 5 (compound 134A) is a potent p53 activator with a SC150 value of <0.05 mM. p53 Activator 5 can bind to mutant p53 and restore the ability of the p53 mutant to bind DNA. p53 Activator 5 shows anti-tumor activity[1].

 Names

Name p53 Activator 5

 p53 Activator 5 Biological Activity

Description p53 Activator 5 (compound 134A) is a potent p53 activator with a SC150 value of <0.05 mM. p53 Activator 5 can bind to mutant p53 and restore the ability of the p53 mutant to bind DNA. p53 Activator 5 shows anti-tumor activity[1].
Related Catalog
References

[1]. VU, Binh, et al. Methods and compounds for restoring mutant p53 function, WO2021061643.

 Chemical & Physical Properties

Molecular Formula C29H32F6N4O
Molecular Weight 566.58
InChIKey PEPYNUAHMQWTFP-UHFFFAOYSA-N
SMILES COc1cc(C(F)(F)F)ccc1NCC#Cc1cc2c(NC3CCC(N(C)C)CC3)cccc2n1CC(F)(F)F
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