p53 Activator 5 structure
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Common Name | p53 Activator 5 | ||
|---|---|---|---|---|
| CAS Number | 2636840-37-2 | Molecular Weight | 566.58 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C29H32F6N4O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of p53 Activator 5p53 Activator 5 (compound 134A) is a potent p53 activator with a SC150 value of <0.05 mM. p53 Activator 5 can bind to mutant p53 and restore the ability of the p53 mutant to bind DNA. p53 Activator 5 shows anti-tumor activity[1]. |
| Name | p53 Activator 5 |
|---|
| Description | p53 Activator 5 (compound 134A) is a potent p53 activator with a SC150 value of <0.05 mM. p53 Activator 5 can bind to mutant p53 and restore the ability of the p53 mutant to bind DNA. p53 Activator 5 shows anti-tumor activity[1]. |
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| Related Catalog | |
| References |
[1]. VU, Binh, et al. Methods and compounds for restoring mutant p53 function, WO2021061643. |
| Molecular Formula | C29H32F6N4O |
|---|---|
| Molecular Weight | 566.58 |
| InChIKey | PEPYNUAHMQWTFP-UHFFFAOYSA-N |
| SMILES | COc1cc(C(F)(F)F)ccc1NCC#Cc1cc2c(NC3CCC(N(C)C)CC3)cccc2n1CC(F)(F)F |