Etamsylate

Modify Date: 2024-01-01 22:19:48

Etamsylate structure	Common Name	Etamsylate
	CAS Number	2624-44-4	Molecular Weight	263.311
	Density	N/A	Boiling Point	496.4ºC at 760 mmHg
	Molecular Formula	C₁₀H₁₇NO₅S	Melting Point	127-131ºC
	MSDS	N/A	Flash Point	254ºC

Use of Etamsylate

Ethamsylate is a haemostatic drug, also inhibits biosynthesis and action of those prostaglandins.

Name	2,5-Dihydroxybenzenesulfonic acid N-ethylethanamine (1:1)
Synonym	More Synonyms

Description	Ethamsylate is a haemostatic drug, also inhibits biosynthesis and action of those prostaglandins.
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Prostaglandin Receptor Research Areas >> Cardiovascular Disease

Boiling Point	496.4ºC at 760 mmHg
Melting Point	127-131ºC
Molecular Formula	C₁₀H₁₇NO₅S
Molecular Weight	263.311
Flash Point	254ºC
Exact Mass	263.082733
PSA	115.24000
LogP	2.43200
Vapour Pressure	1.13E-10mmHg at 25°C
Storage condition	2~8 ℃

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DB6145000

CHEMICAL NAME :: Benzenesulfonic acid, 2,5-dihydroxy-, compd. with diethylamine

CAS REGISTRY NUMBER :: 2624-44-4

LAST UPDATED :: 199806

DATA ITEMS CITED :: 13

MOLECULAR FORMULA :: C6-H6-O5-S.C4-H11-N

MOLECULAR WEIGHT :: 263.34

WISWESSER LINE NOTATION :: WSQR BQ EQ &2M2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 7500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 5250 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1350 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intramuscular

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >4 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 8300 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 29750 mg/kg

TOXIC EFFECTS :: Autonomic Nervous System - other (direct) parasympathomimetic Behavioral - excitement

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 6040 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 760 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intramuscular

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >4 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Mammal - cat

DOSE/DURATION :: 1 gm/kg

TOXIC EFFECTS :: Vascular - BP lowering not characterized in autonomic section Lungs, Thorax, or Respiration - dyspnea

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 3500 mg/kg

TOXIC EFFECTS :: Autonomic Nervous System - other (direct) parasympathomimetic Behavioral - excitement

MUTATION DATA

TYPE OF TEST :: Sex chromosome loss and nondisjunction

TEST SYSTEM :: Mold - Aspergillus nidulans

DOSE/DURATION :: 1 mg/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 26,159,1974

Hazard Codes	Xi
HS Code	2921199090

HS Code	2922299090
Summary	2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Application and equivalence assessment for determining ethamsylate by using potassium ferricyanide as spectroscopic probe reagent.

Anal. Sci. 26(11) , 1163-7, (2010)

In this paper, a novel method has been established to determine ethamsylate using potassium ferricyanide as a spectroscopic probe reagent. It has been demonstrated that Fe(III) is reduced to Fe(II) by...

Simultaneous determination of aminomethylbenzoic acid, cefminox sodium and etamsylate in human urine by capillary electrophoresis.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 878(21) , 1899-903, (2010)

A sensitive and selective capillary electrophoresis method is developed, for the first time, for effective separation and simultaneous determination of aminomethylbezoic acid (PAMBA), cefminox sodium ...

A novel visible spectrophotometric method for the determination of ethamsylate in pharmaceutical preparations and biological samples.

Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 75(3) , 1013-7, (2010)

A highly sensitive visible spectrophotometric method has been developed to determine ethamsylate in this paper, which is based on using Cu(II) as spectroscopic probe reagent. The study indicates that ...

Diethylamine 2,5-Dihydroxybenzenesulfonate

1-Hydroxy-4-oxo-2,5-cyclohexadiene-1-sulfonic Acid Compd with Diethylamine

2,5-Dihydroxybenzenesulfonic acid - N-ethylethanamine (1:1)

MFCD00867499

Etamsylate

EINECS 220-090-7

Ethamsylate

2,5-Dihydroxybenzenesulfonic Acid Compd with N-Ethylethanamine

Benzenesulfonic acid, 2,5-dihydroxy-, compd. with N-ethylethanamine (1:1)

Benzenesulfonic acid,2,5-dihydroxy-,compd. with N-ethylethanamine

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Etamsylate
Price: ￥158.0/25g ￥478.0/100g
Purity: 97.0%
Stocking Period: 2 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: Etamsylate
Price: $300.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Etamsylate
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Zhejiang Hangyu API Co., Ltd
China
Product Name: Pharmaceutical Intermediates
Price: ￥Inquiry/1kg
Purity: 99.5%
Stocking Period: Inquiry
Contact: Vinnie

Henan Tianfu Chemical Co., Ltd.
China
Product Name: Etamsylate API
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson

Get all suppliers and price by the below link:

Etamsylate suppliers

Price: $66/10mM*1mLinDMSO

Reference only. check more Etamsylate price

Dichloromethane
CAS#:75-09-2

Polyacrylic acid
CAS#:9003-01-4

sodium carbonate
CAS#:497-19-8

Silicon dioxide
CAS#:7631-86-9

Triethanolamine
CAS#:102-71-6

Demeton
CAS#:126-75-0

Water
CAS#:7732-18-5

4-(4-Piperidinyl)morpholine dihydrochloride
CAS#:53617-35-9

Diclofenac sodium
CAS#:15307-79-6

Budesonide
CAS#:51372-29-3

Etamsylate

Use of Etamsylate

Names

Etamsylate Biological Activity

Chemical & Physical Properties

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

Safety Information

Customs

Articles25

Synonyms