Poly-L-lysine hydrochloride
Poly-L-lysine hydrochloride structure
|
Common Name | Poly-L-lysine hydrochloride | ||
|---|---|---|---|---|
| CAS Number | 26124-78-7 | Molecular Weight | N/A | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | (C6H14N2O2)x.(HCl)x | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
Use of Poly-L-lysine hydrochloridePoly-L-lysine hydrochloride is a nonspecific attachment factor for cells useful in promoting cell adhesion to solid substrates by enhancing electrostatic interaction between negatively charged ions of the cell membrane and the culture surface. Poly-L-lysine is a strong-attraction regulator that promotes liquid-liquid phase separation (LLPS) at low concentrations but suppresses LLPS at high concentrations. Antibacterial cationic peptide.[1]. |
| Name | POLY-L-LYSINE HYDROCHLORIDE |
|---|---|
| Synonym | More Synonyms |
| Description | Poly-L-lysine hydrochloride is a nonspecific attachment factor for cells useful in promoting cell adhesion to solid substrates by enhancing electrostatic interaction between negatively charged ions of the cell membrane and the culture surface. Poly-L-lysine is a strong-attraction regulator that promotes liquid-liquid phase separation (LLPS) at low concentrations but suppresses LLPS at high concentrations. Antibacterial cationic peptide.[1]. |
|---|---|
| Related Catalog | |
| In Vitro | Poly-L-lysine is a food-grade antimicrobial peptide that forms complexes with proteins. Such complexes are potential carriers for targeted delivery of agents. Electrostatic potential modelling of EPL was employed to describe the interaction affinity. A three-dimensional phase boundary curve was established which divided the complexation into a nano-scale and phase separation[2]. |
| References |
| Molecular Formula | (C6H14N2O2)x.(HCl)x |
|---|---|
| Storage condition | −20°C |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
|
Tumor accumulation and antitumor efficacy of docetaxel-loaded core-shell-corona micelles with shell-specific redox-responsive cross-links
Biomaterials 33 , 1489-1499, (2012) A robust core-shell-corona micelle bearing redox-responsive shell-specific cross-links was evaluated as a carrier of docetaxel (DTX) for cancer therapy. The polymer micelles of poly(ethylene glycol)- ... |
|
|
Improving covalent cell encapsulation with temporarily reactive polyelectrolytes.
J. Mater. Sci. Mater. Med. 23(1) , 181-93, (2011) Calcium alginate/poly-L-lysine beads were coated with either 50% hydrolyzed poly(methyl vinyl ether-alt-maleic anhydride) (PMM(50)), or with poly(vinyl dimethyl azlactone-co-methacrylic acid) (50:50, ... |
|
|
Enhancement of airway gene transfer by DNA nanoparticles using a pH-responsive block copolymer of polyethylene glycol and poly-L-lysine.
Biomaterials 33(7) , 2361-71, (2011) Highly compacted DNA nanoparticles, composed of single molecules of plasmid DNA compacted with block copolymers of polyethylene glycol and poly-L-lysine (PEG-CK(30)), have shown considerable promise i... |
| MFCD00081870 |