Tenofovir-C3-O-C12-trimethylsilylacetylene ammonium

Modify Date: 2024-01-18 22:12:23

Tenofovir-C3-O-C12-trimethylsilylacetylene ammonium structure	Common Name	Tenofovir-C3-O-C12-trimethylsilylacetylene ammonium
	CAS Number	2611373-74-9	Molecular Weight	626.84
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₉H₅₅N₆O₅PSi	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Tenofovir-C3-O-C12-trimethylsilylacetylene ammonium

Tenofovir-C3-O-C12-trimethylsilylacetylene (ammonium) exhibits substantially longer t1/2 values than tenofovir in human liver microsomes, potent anti-HIV activity in vitro, and enhances pharmacokinetic properties in vivo.

Name	Tenofovir-C3-O-C12-trimethylsilylacetylene ammonium

Description	Tenofovir-C3-O-C12-trimethylsilylacetylene (ammonium) exhibits substantially longer t1/2 values than tenofovir in human liver microsomes, potent anti-HIV activity in vitro, and enhances pharmacokinetic properties in vivo.
Related Catalog	Signaling Pathways >> Anti-infection >> HIV Research Areas >> Infection
References	[1]. Pribut N, et al. ω-Functionalized Lipid Prodrugs of HIV NtRTI Tenofovir with Enhanced Pharmacokinetic Properties. J Med Chem. 2021 Sep 9;64(17):12917-12937.

Molecular Formula	C₂₉H₅₅N₆O₅PSi
Molecular Weight	626.84

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Tenofovir-C3-O-C12-trimethylsilylacetylene ammonium

Use of Tenofovir-C3-O-C12-trimethylsilylacetylene ammonium

Names

Biological Activity

Chemical & Physical Properties