2611373-74-9

2611373-74-9 structure

Name: Tenofovir-C3-O-C12-trimethylsilylacetylene ammonium
Chemical Name: Tenofovir-C3-O-C12-trimethylsilylacetylene ammonium
CAS Number: 2611373-74-9
Molecular Formula: C₂₉H₅₅N₆O₅PSi
Molecular Weight: 626.84
Catalog: Signaling Pathways Anti-infection HIV
Create Date: 2022-01-07 20:45:19
Modify Date: 2025-08-27 16:02:56
Tenofovir-C3-O-C12-trimethylsilylacetylene (ammonium) exhibits substantially longer t1/2 values than tenofovir in human liver microsomes, potent anti-HIV activity in vitro, and enhances pharmacokinetic properties in vivo.

Name	Tenofovir-C3-O-C12-trimethylsilylacetylene ammonium

Description	Tenofovir-C3-O-C12-trimethylsilylacetylene (ammonium) exhibits substantially longer t1/2 values than tenofovir in human liver microsomes, potent anti-HIV activity in vitro, and enhances pharmacokinetic properties in vivo.
Related Catalog	Signaling Pathways >> Anti-infection >> HIV Research Areas >> Infection
References	[1]. Pribut N, et al. ω-Functionalized Lipid Prodrugs of HIV NtRTI Tenofovir with Enhanced Pharmacokinetic Properties. J Med Chem. 2021 Sep 9;64(17):12917-12937.

Molecular Formula	C₂₉H₅₅N₆O₅PSi
Molecular Weight	626.84