RBP4 ligand-1

Modify Date: 2024-01-02 09:53:00

RBP4 ligand-1 structure	Common Name	RBP4 ligand-1
	CAS Number	260553-24-0	Molecular Weight	414.81
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₈H₁₈ClF₃N₄O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of RBP4 ligand-1

RBP4 ligand-1 is a non-retinoid ligands for (RBP4) retinol-binding protein 4. The hRBP4SPA IC50 and RBP4–TTR FRET IC50 values are 0.23±0.11 and 0.13±0.12 μM in the radioligand binding assay and FRET assay, respectively[1].

Name	RBP4 ligand-1

Description	RBP4 ligand-1 is a non-retinoid ligands for (RBP4) retinol-binding protein 4. The hRBP4SPA IC50 and RBP4–TTR FRET IC50 values are 0.23±0.11 and 0.13±0.12 μM in the radioligand binding assay and FRET assay, respectively[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
In Vitro	Retinol-Binding Protein 4 (RBP4) is a physiological carrier of retinol (vitamin A) in blood, delivering retinol from the liver to peripheral tissues.RBP4 ligand-1 has the ability to disrupt the RBP4–TTR protein–protein interaction (hRPB4–TTR). The RBP4–TTR FRET IC50 is 0.13±0.12 μM in FRET assay[1].
In Vivo	RBP4配体
References	[1]. Yingcai Wang, et al. Structure-assisted discovery of the first non-retinoid ligands for Retinol-Binding Protein 4. Bioorg Med Chem Lett. 2014 Jul 1;24(13):2885-91.

Molecular Formula	C₁₈H₁₈ClF₃N₄O₂
Molecular Weight	414.81

RBP4 ligand-1

Use of RBP4 ligand-1

Names

RBP4 ligand-1 Biological Activity

Chemical & Physical Properties