Ligustroflavone

Modify Date: 2025-08-21 00:21:26

Ligustroflavone Structure
Ligustroflavone structure
Common Name Ligustroflavone
CAS Number 260413-62-5 Molecular Weight 724.66
Density 1.7±0.1 g/cm3 Boiling Point 1028.5±65.0 °C at 760 mmHg
Molecular Formula C33H40O18 Melting Point N/A
MSDS N/A Flash Point 325.2±27.8 °C

 Use of Ligustroflavone


Ligustroflavone, extracted from Ligustrum lucidum, is a potential candidate as calcium-sensing receptor (CaSR) antagonist. Ligustroflavone exhibits protective effects against diabetic osteoporosis in mice[1].

 Names

Name 5-Hydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yl 6-deoxy-α-L-mannopyranosyl-(1->2)-[6-deoxy-α-L-mannopyranosyl-(1->6)]-β-D-glucopyranoside
Synonym More Synonyms

 Ligustroflavone Biological Activity

Description Ligustroflavone, extracted from Ligustrum lucidum, is a potential candidate as calcium-sensing receptor (CaSR) antagonist. Ligustroflavone exhibits protective effects against diabetic osteoporosis in mice[1].
Related Catalog
Target

CaSR[1].

References

[1]. Feng R, et al. Protective Effects of Ligustroflavone, an Active Compound from Ligustrum lucidum, on Diabetes-Induced Osteoporosis in Mice: A Potential Candidate as Calcium-Sensing Receptor Antagonist. Am J Chin Med. 2019;47(2):457-476.

 Chemical & Physical Properties

Density 1.7±0.1 g/cm3
Boiling Point 1028.5±65.0 °C at 760 mmHg
Molecular Formula C33H40O18
Molecular Weight 724.66
Flash Point 325.2±27.8 °C
Exact Mass 724.221436
PSA 287.89000
LogP 1.56
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.714
InChIKey NULBHTHMVOCGOE-ZBCCAYPVSA-N
SMILES CC1OC(OCC2OC(Oc3cc(O)c4c(=O)cc(-c5ccc(O)cc5)oc4c3)C(OC3OC(C)C(O)C(O)C3O)C(O)C2O)C(O)C(O)C1O

 Safety Information

Safety Phrases 24/25

 Synonyms

5-Hydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yl 6-deoxy-α-L-mannopyranosyl-(1->2)-[6-deoxy-α-L-mannopyranosyl-(1->6)]-β-D-glucopyranoside
ligustroflavone
4H-1-Benzopyran-4-one, 7-[[O-6-deoxy-α-L-mannopyranosyl-(1->2)-O-[6-deoxy-α-L-mannopyranosyl-(1->6)]-β-D-glucopyranosyl]oxy]-5-hydroxy-2-(4-hydroxyphenyl)-
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