Solnatide

Modify Date: 2024-01-09 11:24:07

Solnatide structure	Common Name	Solnatide
	CAS Number	259206-53-6	Molecular Weight	1923.11
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₈₂H₁₁₉N₂₃O₂₇S₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Solnatide

Solnatide (AP 301) is an inhaled synthetic peptide agent composed of 17 natural amino acids. Solnatide can directly activate the epithelial sodium channel. Solnatide can be used for the research of lung function[1][2].

Name	Solnatide

Description	Solnatide (AP 301) is an inhaled synthetic peptide agent composed of 17 natural amino acids. Solnatide can directly activate the epithelial sodium channel. Solnatide can be used for the research of lung function[1][2].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> Sodium Channel Research Areas >> Metabolic Disease
In Vivo	Solnatide (100, 300, 500 µg; once daily for 3 consecutive days) reduces pulmonary edema, increases occludin expression, and improves gas-blood barrier function during acute hypobaric hypoxia and exercise in rats[2]. Animal Model: Sprague-Dawley rats[2] Dosage: 100, 300, 500 µg Administration: Once daily for 3 consecutive days Result: Significantly reduced BAL fluid protein and lung water content. Had intact lungs and showed less hemorrhage and disruption of the alveolar-capillary barrier. Showed high expression of occludin in solnatide-treated animals.