259206-53-6
259206-53-6 structure
- Name: Solnatide
- Chemical Name: Solnatide
- CAS Number: 259206-53-6
- Molecular Formula: C82H119N23O27S2
- Molecular Weight: 1923.11
- Catalog: Signaling Pathways Membrane Transporter/Ion Channel Sodium Channel
- Create Date: 2023-02-05 13:23:09
- Modify Date: 2024-01-09 11:24:07
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Solnatide (AP 301) is an inhaled synthetic peptide agent composed of 17 natural amino acids. Solnatide can directly activate the epithelial sodium channel. Solnatide can be used for the research of lung function[1][2].
| Name | Solnatide |
|---|
| Description | Solnatide (AP 301) is an inhaled synthetic peptide agent composed of 17 natural amino acids. Solnatide can directly activate the epithelial sodium channel. Solnatide can be used for the research of lung function[1][2]. |
|---|---|
| Related Catalog | |
| In Vivo | Solnatide (100, 300, 500 µg; once daily for 3 consecutive days) reduces pulmonary edema, increases occludin expression, and improves gas-blood barrier function during acute hypobaric hypoxia and exercise in rats[2]. Animal Model: Sprague-Dawley rats[2] Dosage: 100, 300, 500 µg Administration: Once daily for 3 consecutive days Result: Significantly reduced BAL fluid protein and lung water content. Had intact lungs and showed less hemorrhage and disruption of the alveolar-capillary barrier. Showed high expression of occludin in solnatide-treated animals. |
| Molecular Formula | C82H119N23O27S2 |
|---|---|
| Molecular Weight | 1923.11 |