Liensinine

Modify Date: 2024-01-02 10:53:03

Liensinine structure	Common Name	Liensinine
	CAS Number	2586-96-1	Molecular Weight	610.739
	Density	1.2±0.1 g/cm3	Boiling Point	722.0±60.0 °C at 760 mmHg
	Molecular Formula	C₃₇H₄₂N₂O₆	Melting Point	95-99ºC
	MSDS	N/A	Flash Point	390.4±32.9 °C

Use of Liensinine

Liensinine is an autophagy/mitophagy inhibitor. Liensinine, a major isoquinoline alkaloid, extracted from the seed embryo of Nelumbo nucifera Gaertn, has a wide range of biological activities, including anti-arrhythmias, anti-hypertension, anti-pulmonary fibrosis, relaxation on vascular smooth muscle, etc[1].

Name	Liensinine
Synonym	More Synonyms

Description	Liensinine is an autophagy/mitophagy inhibitor. Liensinine, a major isoquinoline alkaloid, extracted from the seed embryo of Nelumbo nucifera Gaertn, has a wide range of biological activities, including anti-arrhythmias, anti-hypertension, anti-pulmonary fibrosis, relaxation on vascular smooth muscle, etc[1].
Related Catalog	Research Areas >> Cancer Research Areas >> Cardiovascular Disease Signaling Pathways >> Autophagy >> Autophagy Signaling Pathways >> Autophagy >> Mitophagy
References	[1]. Zhou J, et al. A novel autophagy/mitophagy inhibitor liensinine sensitizes breast cancer cells to chemotherapy through DNM1L-mediated mitochondrial fission. Autophagy. 2015;11(8):1259-79.

Density	1.2±0.1 g/cm3
Boiling Point	722.0±60.0 °C at 760 mmHg
Melting Point	95-99ºC
Molecular Formula	C₃₇H₄₂N₂O₆
Molecular Weight	610.739
Flash Point	390.4±32.9 °C
Exact Mass	610.304260
PSA	83.86000
LogP	4.84
Vapour Pressure	0.0±2.4 mmHg at 25°C
Index of Refraction	1.618

Hazard Codes	Xi

4-{[(1R)-6,7-Dimethoxy-2-methyl-1,2,3,4-tetrahydro-1-isoquinolinyl]methyl}-2-{[(1R)-1-(4-hydroxybenzyl)-6-methoxy-2-methyl-1,2,3,4-tetrahydro-7-isoquinolinyl]oxy}phenol

4-{[(1R)-6,7-Dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-1-yl]methyl}-2-{[(1R)-1-(4-hydroxybenzyl)-6-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-7-yl]oxy}phenol

Hiensinine

Phenol, 4-[[(1R)-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl]methyl]-2-[[(1R)-1,2,3,4-tetrahydro-1-[(4-hydroxyphenyl)methyl]-6-methoxy-2-methyl-7-isoquinolinyl]oxy]-

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Liensinine
Price: ￥738.0/20mg
Purity: 98.0%
Stocking Period: 1 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: Liensinine
Price: $280.0/20mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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Price: ￥990/5 mg

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Liensinine

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