PROTAC BTK Degrader-3

Modify Date: 2024-04-06 14:42:39

PROTAC BTK Degrader-3 Structure
PROTAC BTK Degrader-3 structure
Common Name PROTAC BTK Degrader-3
CAS Number 2563861-90-3 Molecular Weight 752.82
Density N/A Boiling Point N/A
Molecular Formula C41H40N10O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PROTAC BTK Degrader-3


PROTAC BTK Degrader-3 is a potent BTK degrader with a DC50 value of 10.9 nM of BTK degradation in Mino cells. PROTAC BTK Degrader-3 has the potential for B-cell malignancies, including chronic lymphoid malignancies research[1].

 Names

Name PROTAC BTK Degrader-3

 PROTAC BTK Degrader-3 Biological Activity

Description PROTAC BTK Degrader-3 is a potent BTK degrader with a DC50 value of 10.9 nM of BTK degradation in Mino cells. PROTAC BTK Degrader-3 has the potential for B-cell malignancies, including chronic lymphoid malignancies research[1].
Related Catalog
References

[1]. Zhangchen, et al. Salt of compound for degrading btk, crystal form thereof, and use thereof in medicine. Patent WO2022052950A1.

 Chemical & Physical Properties

Molecular Formula C41H40N10O5
Molecular Weight 752.82
InChIKey BORJZCDAUJWRDI-UHFFFAOYSA-N
SMILES Nc1ncnc2c1c(-c1ccc(Oc3ccccc3)cc1)nn2C1CCN(C2CN(C3CN(c4ccc5c(c4)C(=O)N(C4CCC(=O)NC4=O)C5=O)C3)C2)CC1
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