PROTAC BTK Degrader-3

Names

[ Name ]:
PROTAC BTK Degrader-3

Biological Activity

[Description]:

PROTAC BTK Degrader-3 is a potent BTK degrader with a DC50 value of 10.9 nM of BTK degradation in Mino cells. PROTAC BTK Degrader-3 has the potential for B-cell malignancies, including chronic lymphoid malignancies research[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Btk

Signaling Pathways >> PROTAC >> PROTAC

[References]

[1]. Zhangchen, et al. Salt of compound for degrading btk, crystal form thereof, and use thereof in medicine. Patent WO2022052950A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C₄₁H₄₀N₁₀O₅

[ Molecular Weight ]:
752.82

Related Compounds

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