ABCG2-IN-1

Modify Date: 2024-04-09 11:26:46

ABCG2-IN-1 Structure
ABCG2-IN-1 structure
Common Name ABCG2-IN-1
CAS Number 2559759-40-7 Molecular Weight 468.59
Density N/A Boiling Point N/A
Molecular Formula C26H36N4O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of ABCG2-IN-1


ABCG2-IN-1 (compound K2), a Ko143 analog, is an orally active ABCG2 inhibitor with an IC50 of 0.13 μM. ABCG2-IN-1 has favorable oral pharmacokinetic profiles in mice[1].

 Names

Name ABCG2-IN-1

 ABCG2-IN-1 Biological Activity

Description ABCG2-IN-1 (compound K2), a Ko143 analog, is an orally active ABCG2 inhibitor with an IC50 of 0.13 μM. ABCG2-IN-1 has favorable oral pharmacokinetic profiles in mice[1].
Related Catalog
Target

IC50: 0.13 μM (ABCG2)[1]

References

[1]. Junjie Zhu, et al. Metabolism-guided development of Ko143 analogs as ABCG2 inhibitors. Eur J Med Chem. 2023 Nov 5;259:115666.  

 Chemical & Physical Properties

Molecular Formula C26H36N4O4
Molecular Weight 468.59
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