ABCG2-IN-1

Modify Date: 2025-09-12 11:19:32

ABCG2-IN-1 structure	Common Name	ABCG2-IN-1
	CAS Number	2559759-40-7	Molecular Weight	468.59
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₆H₃₆N₄O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of ABCG2-IN-1

ABCG2-IN-1 (compound K2), a Ko143 analog, is an orally active ABCG2 inhibitor with an IC50 of 0.13 μM. ABCG2-IN-1 has favorable oral pharmacokinetic profiles in mice[1].

Name	ABCG2-IN-1

Description	ABCG2-IN-1 (compound K2), a Ko143 analog, is an orally active ABCG2 inhibitor with an IC50 of 0.13 μM. ABCG2-IN-1 has favorable oral pharmacokinetic profiles in mice[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Membrane Transporter/Ion Channel >> BCRP
Target	IC50: 0.13 μM (ABCG2)[1]
References	[1]. Junjie Zhu, et al. Metabolism-guided development of Ko143 analogs as ABCG2 inhibitors. Eur J Med Chem. 2023 Nov 5;259:115666.

Molecular Formula	C₂₆H₃₆N₄O₄
Molecular Weight	468.59

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