2559759-40-7

2559759-40-7 structure
2559759-40-7 structure
  • Name: ABCG2-IN-1
  • Chemical Name: ABCG2-IN-1
  • CAS Number: 2559759-40-7
  • Molecular Formula: C26H36N4O4
  • Molecular Weight: 468.59
  • Catalog: Signaling Pathways Membrane Transporter/Ion Channel BCRP
  • Create Date: 2023-11-04 16:04:35
  • Modify Date: 2024-04-09 11:26:46
  • ABCG2-IN-1 (compound K2), a Ko143 analog, is an orally active ABCG2 inhibitor with an IC50 of 0.13 μM. ABCG2-IN-1 has favorable oral pharmacokinetic profiles in mice[1].

Name ABCG2-IN-1
Description ABCG2-IN-1 (compound K2), a Ko143 analog, is an orally active ABCG2 inhibitor with an IC50 of 0.13 μM. ABCG2-IN-1 has favorable oral pharmacokinetic profiles in mice[1].
Related Catalog
Target

IC50: 0.13 μM (ABCG2)[1]

References

[1]. Junjie Zhu, et al. Metabolism-guided development of Ko143 analogs as ABCG2 inhibitors. Eur J Med Chem. 2023 Nov 5;259:115666.  

Molecular Formula C26H36N4O4
Molecular Weight 468.59
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