A-123189

Modify Date: 2024-01-27 22:02:20

A-123189 Structure
A-123189 structure
Common Name A-123189
CAS Number 255713-53-2 Molecular Weight 476.59
Density 1.261±0.06 g/cm3(Predicted) Boiling Point N/A
Molecular Formula C26H28N4O3S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of A-123189


A-123189 is a selective and potent α1D antagonist with Kis of 0.312 and 0.17 for human α1D and rat α1D, respectively. A-123189 displays selectivities between 10- to 20-fold for the α1D receptor over the human α1A and rat α1A receptors[1].

 Names

Name A-123189
Synonym More Synonyms

 A-123189 Biological Activity

Description A-123189 is a selective and potent α1D antagonist with Kis of 0.312 and 0.17 for human α1D and rat α1D, respectively. A-123189 displays selectivities between 10- to 20-fold for the α1D receptor over the human α1A and rat α1A receptors[1].
Related Catalog
References

[1]. K P Briski, et al. Antagonism of type II, but not type I glucocorticoid receptors results in elevated basal luteinizing hormone release in male rats. Bioorganic & Medicinal Chemistry Letters, Volume 11, Issue 9, 7 May 2001, Pages 1119-1121.

 Chemical & Physical Properties

Density 1.261±0.06 g/cm3(Predicted)
Molecular Formula C26H28N4O3S
Molecular Weight 476.59

 Synonyms

A 123189
A123189