Fibrinopeptide A human
Modify Date: 2025-10-24 16:48:41
Fibrinopeptide A human structure
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Common Name | Fibrinopeptide A human | ||
|---|---|---|---|---|
| CAS Number | 25422-31-5 | Molecular Weight | 1536.56000 | |
| Density | 1.53 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C63H97N19O26 | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
Use of Fibrinopeptide A humanFibrinopeptide A, human is a 16-residue short polypeptide cleaved from fibrinogen by thrombin. Fibrinopeptide A, human locates at the NH2-termini of the Aα chain. |
| Name | Fibrinopeptide A |
|---|---|
| Synonym | More Synonyms |
| Description | Fibrinopeptide A, human is a 16-residue short polypeptide cleaved from fibrinogen by thrombin. Fibrinopeptide A, human locates at the NH2-termini of the Aα chain. |
|---|---|
| Related Catalog | |
| In Vitro | The conversion of monomeric fibrinogen into polymeric fibrin is mediated by thrombin, which binds to the central region of fibrinogen and catalyzes cleavage of the 2 short peptides, the 16-residue fibrinopeptide A (FpA) and the 14-residue fibrinopeptide B (FpB), located at the NH2-termini of the Aα and Bβ chains, respectively[1]. |
| In Vivo | Fibrinopeptide A (FPA) is a small polypeptide cleaved from fibrinogen by thrombin, has a short half-life, and is considered a sensitive biochemical marker of thrombin activity, fibrin generation, and ongoing thrombosis[2]. |
| References |
| Density | 1.53 g/cm3 |
|---|---|
| Molecular Formula | C63H97N19O26 |
| Molecular Weight | 1536.56000 |
| Exact Mass | 1535.69000 |
| PSA | 731.15000 |
| InChIKey | JWICNZAGYSIBAR-UHFFFAOYSA-N |
| SMILES | CC(C)CC(NC(=O)C(Cc1ccccc1)NC(=O)C(CC(=O)O)NC(=O)CNC(=O)C(CCC(=O)O)NC(=O)CNC(=O)C(CO)NC(=O)C(CC(=O)O)NC(=O)C(C)N)C(=O)NC(C)C(=O)NC(CCC(=O)O)C(=O)NCC(=O)NCC(=O)NCC(=O)NC(C(=O)NC(CCCN=C(N)N)C(=O)O)C(C)C |
| Storage condition | −20°C |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
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Thromboprophylaxis in patients receiving chemotherapy.
N. Engl. J. Med. 366(19) , 1839; author reply 1839-40, (2012)
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Routine heparin for patients with cancer? One answer, more questions.
N. Engl. J. Med. 366(7) , 661-2, (2012)
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Congenital dysfibrinogenemia Aα Gly13Glu associated with bleeding during pregnancy.
Thromb. Res. 127(3) , 277-8, (2011)
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| fibrinopeptide a, human |
| MFCD00076437 |
| ADSGEGDFLAEGGGVR |
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