Fibrinopeptide A human

Modify Date: 2024-01-01 17:53:38

Fibrinopeptide A human Structure
Fibrinopeptide A human structure
Common Name Fibrinopeptide A human
CAS Number 25422-31-5 Molecular Weight 1536.56000
Density 1.53 g/cm3 Boiling Point N/A
Molecular Formula C63H97N19O26 Melting Point N/A
MSDS USA Flash Point N/A

 Use of Fibrinopeptide A human


Fibrinopeptide A, human is a 16-residue short polypeptide cleaved from fibrinogen by thrombin. Fibrinopeptide A, human locates at the NH2-termini of the Aα chain.

 Names

Name Fibrinopeptide A
Synonym More Synonyms

 Fibrinopeptide A human Biological Activity

Description Fibrinopeptide A, human is a 16-residue short polypeptide cleaved from fibrinogen by thrombin. Fibrinopeptide A, human locates at the NH2-termini of the Aα chain.
Related Catalog
In Vitro The conversion of monomeric fibrinogen into polymeric fibrin is mediated by thrombin, which binds to the central region of fibrinogen and catalyzes cleavage of the 2 short peptides, the 16-residue fibrinopeptide A (FpA) and the 14-residue fibrinopeptide B (FpB), located at the NH2-termini of the Aα and Bβ chains, respectively[1].
In Vivo Fibrinopeptide A (FPA) is a small polypeptide cleaved from fibrinogen by thrombin, has a short half-life, and is considered a sensitive biochemical marker of thrombin activity, fibrin generation, and ongoing thrombosis[2].
References

[1]. Riedel T, et al. Fibrinopeptides A and B release in the process of surface fibrin formation. Blood. 2011 Feb 3;117(5):1700-6.

[2]. Manolis AS, et al. Plasma level changes of fibrinopeptide A after uncomplicated coronary angioplasty. Clin Cardiol. 1993 Jul;16(7):548-52.

 Chemical & Physical Properties

Density 1.53 g/cm3
Molecular Formula C63H97N19O26
Molecular Weight 1536.56000
Exact Mass 1535.69000
PSA 731.15000
Storage condition −20°C

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport
WGK Germany 3

 Synonyms

fibrinopeptide a, human
MFCD00076437
ADSGEGDFLAEGGGVR