ZC0101

Modify Date: 2024-01-09 19:25:04

ZC0101 structure	Common Name	ZC0101
	CAS Number	2541604-52-6	Molecular Weight	293.32
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₇H₁₅N₃O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of ZC0101

ZC0101 is a potent, orally active IDO1 and TrxR dual inhibitor with IC50 values of 0.084 μM and 7.98 μM, respectively. ZC0101 effectively induces apoptosis and ROS accumulation in cancer cells[1].

Name	ZC0101

Description	ZC0101 is a potent, orally active IDO1 and TrxR dual inhibitor with IC50 values of 0.084 μM and 7.98 μM, respectively. ZC0101 effectively induces apoptosis and ROS accumulation in cancer cells[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Indoleamine 2,3-Dioxygenase (IDO) Signaling Pathways >> Protein Tyrosine Kinase/RTK >> ROS
Target	IDO1:0.084 μM (IC50) TrxR:7.98 μM (IC50)
In Vivo	ZC0101 (60 mg/kg; p.o.; once) effectively suppresses IDO1 activity in vivo[1].
References	[1]. Fan QZ, et al. Design, synthesis, and biological evaluation of a novel indoleamine 2,3-dioxigenase 1 (IDO1) and thioredoxin reductase (TrxR) dual inhibitor. Bioorg Chem. 2020 Dec;105:104401.

Molecular Formula	C₁₇H₁₅N₃O₂
Molecular Weight	293.32

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ZC0101

Use of ZC0101

Names

ZC0101 Biological Activity

Chemical & Physical Properties