Romlusevimab

Modify Date: 2025-08-26 20:15:54

Romlusevimab Structure
Romlusevimab structure
Common Name Romlusevimab
CAS Number 2509447-08-7 Molecular Weight N/A
Density N/A Boiling Point N/A
Molecular Formula N/A Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Romlusevimab


Romlusevimab (BRII-198) is a neutralizing recombinant human IgG1 monoclonal antibody against the spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)[1][2].

 Names

Name Romlusevimab

 Romlusevimab Biological Activity

Description Romlusevimab (BRII-198) is a neutralizing recombinant human IgG1 monoclonal antibody against the spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)[1][2].
Related Catalog
In Vitro Romlusevimab 和 Amubarvimab (HY-P99435) 结合 SARS-CoV-2 刺突蛋白的不同表位[1]。 Romlusevimab 与 Amubarvimab 联合使用时具有累加效应[1] 。
In Vivo Romlusevimab (10 mg/kg,ip,单次)与 Amubarvimab (HY-P99435) 联合使用可在 SARS-CoV-2 感染小鼠模型中保护动物免受 Omicron 感染[1]。
References

[1]. Hoy SM. Amubarvimab/Romlusevimab: First Approval. Drugs. 2022 Aug;82(12):1327-1331.  

[2]. Ji Y, et al. Preclinical characterization of amubarvimab and romlusevimab, a pair of non-competing neutralizing monoclonal antibody cocktail, against SARS-CoV-2. Front Immunol. 2022 Sep 14;13:980435.  

 Chemical & Physical Properties

No Any Chemical & Physical Properties
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