2509447-08-7
2509447-08-7 structure
- Name: Romlusevimab
- Chemical Name: Romlusevimab
- CAS Number: 2509447-08-7
- Molecular Formula:
- Molecular Weight:
- Catalog: Signaling Pathways Anti-infection SARS-CoV
- Create Date: 2023-05-12 10:52:16
- Modify Date: 2025-08-26 20:15:54
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Romlusevimab (BRII-198) is a neutralizing recombinant human IgG1 monoclonal antibody against the spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)[1][2].
| Name | Romlusevimab |
|---|
| Description | Romlusevimab (BRII-198) is a neutralizing recombinant human IgG1 monoclonal antibody against the spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)[1][2]. |
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| Related Catalog | |
| In Vitro | Romlusevimab 和 Amubarvimab (HY-P99435) 结合 SARS-CoV-2 刺突蛋白的不同表位[1]。 Romlusevimab 与 Amubarvimab 联合使用时具有累加效应[1] 。 |
| In Vivo | Romlusevimab (10 mg/kg，ip，单次)与 Amubarvimab (HY-P99435) 联合使用可在 SARS-CoV-2 感染小鼠模型中保护动物免受 Omicron 感染[1]。 |
| References |
[1]. Hoy SM. Amubarvimab/Romlusevimab: First Approval. Drugs. 2022 Aug;82(12):1327-1331. |
| No Any Chemical & Physical Properties |