Tubulin polymerization-IN-22

Modify Date: 2025-08-27 19:19:23

Tubulin polymerization-IN-22 Structure
Tubulin polymerization-IN-22 structure
 Common Name Tubulin polymerization-IN-22
CAS Number 2493052-22-3 Molecular Weight 308.33
Density N/A Boiling Point N/A
Molecular Formula C19H16O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Tubulin polymerization-IN-22


Tubulin polymerization-IN-22 is a tubulin polymerization inhibitor with an IC50 of 8.1 μM. Tubulin polymerization-IN-22 arrests cell cycle at G2/M phase and induces apoptosis[1].

 Names

Name Tubulin polymerization-IN-22

 Tubulin polymerization-IN-22 Biological Activity

Description Tubulin polymerization-IN-22 is a tubulin polymerization inhibitor with an IC50 of 8.1 μM. Tubulin polymerization-IN-22 arrests cell cycle at G2/M phase and induces apoptosis[1].
Related Catalog
In Vitro Tubulin polymerization-IN-22 (Compound 4u) shows antiproliferative activity against human breast cancer cell line (MCF-7) with an IC50 of 1.47 μM[1]. Tubulin polymerization-IN-22 (Compound 4u) is a tubulin polymerization inhibitor by targeting the Colchicine binding site[1].
References

[1]. Guangcheng Wang, et al. Design, synthesis, and anticancer evaluation of benzophenone derivatives bearing naphthalene moiety as novel tubulin polymerization inhibitors. Bioorg Chem. 2020 Nov;104:104265.

 Chemical & Physical Properties

Molecular Formula C19H16O4
Molecular Weight 308.33
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Chemsrc provides Tubulin polymerization-IN-22(CAS#:2493052-22-3) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Tubulin polymerization-IN-22 are included as well.>> amp version: Tubulin polymerization-IN-22

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