HDAC-IN-41
Modify Date: 2025-09-12 14:36:02
HDAC-IN-41 structure
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Common Name | HDAC-IN-41 | ||
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| CAS Number | 2490309-83-4 | Molecular Weight | 446.48 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C20H22N4O6S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of HDAC-IN-41HDAC-IN-41 (Compound 7c) is a selective, orally active class I HDAC inhibitor with IC50 values of 0.62, 1.46 and 0.62 μM against HDAC1, HDAC2 and HDAC3, respectively. HDAC-IN-41 shows NO releasing activity[1]. |
| Name | HDAC-IN-41 |
|---|
| Description | HDAC-IN-41 (Compound 7c) is a selective, orally active class I HDAC inhibitor with IC50 values of 0.62, 1.46 and 0.62 μM against HDAC1, HDAC2 and HDAC3, respectively. HDAC-IN-41 shows NO releasing activity[1]. |
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| Related Catalog | |
| Target |
HDAC1:0.62 μM (IC50) HDAC2:1.46 μM (IC50) HDAC3:0.62 μM (IC50) |
| In Vitro | HDAC-IN-41 (Compound 7c) shows anti-proliferative activity with IC50 values of 0.32 ± 0.06, 0.59 ± 0.09, 0.54 ± 0.05, 1.23 ± 0.06, 2.69 ± 0.15, 0.93 ± 0.08 and 1.03 ± 0.09 μM against HEL, MOLT-4, Jurkat, HeLa, PC-3, HCT116 and A549 cells, respectively[1]. |
| In Vivo | HDAC-IN-41 (Compound 7c) (30 mg/kg/d; p.o., 15 days) inhibits tumor growth in a HCT116 xenograft model in nude mice[1]. |
| References |
| Molecular Formula | C20H22N4O6S |
|---|---|
| Molecular Weight | 446.48 |