Antileishmanial agent-8

Modify Date: 2025-09-27 18:49:49

Antileishmanial agent-8 Structure
Antileishmanial agent-8 structure
 Common Name Antileishmanial agent-8
CAS Number 2477608-96-9 Molecular Weight 296.32
Density N/A Boiling Point N/A
Molecular Formula C18H16O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Antileishmanial agent-8


Antileishmanial agent-8 (compound 18) has potent and selective activity against Leishmania donovani (L. donovani) with an IC50 value of 5.64 μM. Antileishmanial agent-8 has relatively low cytotoxicity in L-6 cells (IC50=73.9 μM)[1].

 Names

Name Antileishmanial agent-8

 Antileishmanial agent-8 Biological Activity

Description Antileishmanial agent-8 (compound 18) has potent and selective activity against Leishmania donovani (L. donovani) with an IC50 value of 5.64 μM. Antileishmanial agent-8 has relatively low cytotoxicity in L-6 cells (IC50=73.9 μM)[1].
Related Catalog
Target

IC50: 5.64 μmol/L (L. donovani)[1]

References

[1]. Bernal FA, et al. (±)-trans-2-phenyl-2,3-dihydrobenzofurans as leishmanicidal agents: Synthesis, in vitro evaluation and SAR analysis. Eur J Med Chem. 2020;205:112493.

 Chemical & Physical Properties

Molecular Formula C18H16O4
Molecular Weight 296.32
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