AL 8810

Modify Date: 2024-01-06 22:13:28

AL 8810 Structure
AL 8810 structure
Common Name AL 8810
CAS Number 246246-19-5 Molecular Weight 402.499
Density 1.2±0.1 g/cm3 Boiling Point 594.6±50.0 °C at 760 mmHg
Molecular Formula C24H31FO4 Melting Point N/A
MSDS USA Flash Point 313.4±30.1 °C

 Use of AL 8810


AL-8810 is an 11β-fluoro analog of PGF2α and acts as a potent and selective antagonist of the PGF2αreceptor (FP receptor)[1].

 Names

Name (5z,13e)-(9s,11s,15r)-9,15,dihydroxy-11-fluoro-15-(2-indanyl)-16,17,18,19,20,pentanor-5,13-prostadienoic acid
Synonym More Synonyms

 AL 8810 Biological Activity

Description AL-8810 is an 11β-fluoro analog of PGF2α and acts as a potent and selective antagonist of the PGF2αreceptor (FP receptor)[1].
Related Catalog
References

[1]. Griffin BW, et al. AL-8810: a novel prostaglandin F2 alpha analog with selective antagonist effects at the prostaglandin F2 alpha (FP) receptor. J Pharmacol Exp Ther. 1999 Sep;290(3):1278-84.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 594.6±50.0 °C at 760 mmHg
Molecular Formula C24H31FO4
Molecular Weight 402.499
Flash Point 313.4±30.1 °C
Exact Mass 402.220642
PSA 77.76000
LogP 4.00
Vapour Pressure 0.0±1.8 mmHg at 25°C
Index of Refraction 1.584

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport
WGK Germany 3

 Articles2

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 Synonyms

al 8810
(5Z)-7-{(1R,2R,3S,5S)-2-[(1E,3R)-3-(2,3-Dihydro-1H-inden-2-yl)-3-hydroxyprop-1-en-1-yl]-3-fluoro-5-hydroxycyclopentyl}hept-5-enoic acid
5-Heptenoic acid, 7-[(1R,2R,3S,5S)-2-[(1E,3R)-3-(2,3-dihydro-1H-inden-2-yl)-3-hydroxy-1-propen-1-yl]-3-fluoro-5-hydroxycyclopentyl]-, (5Z)-
(5Z)-7-{(1R,2R,3S,5S)-2-[(1E,3R)-3-(2,3-Dihydro-1H-inden-2-yl)-3-hydroxy-1-propen-1-yl]-3-fluoro-5-hydroxycyclopentyl}-5-heptenoic acid