Mecbotamab

Modify Date: 2025-09-19 18:46:23

Mecbotamab Structure
Mecbotamab structure
Common Name Mecbotamab
CAS Number 2460400-28-4 Molecular Weight N/A
Density N/A Boiling Point N/A
Molecular Formula N/A Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Mecbotamab


Mecbotamab is a humanized IgG1-κ antibody targeting to AXL receptor tyrosine kinase (AXL). Mecbotamab can serves as a conditionally active biologic (CAB), which can be conjugated with MMAE (HY-15162) via a cleavable linker, to form ADC Mecbotamab vedotin (BA3011)[1][2].

 Names

Name Mecbotamab

 Mecbotamab Biological Activity

Description Mecbotamab is a humanized IgG1-κ antibody targeting to AXL receptor tyrosine kinase (AXL). Mecbotamab can serves as a conditionally active biologic (CAB), which can be conjugated with MMAE (HY-15162) via a cleavable linker, to form ADC Mecbotamab vedotin (BA3011)[1][2].
Related Catalog
References

[1]. Shen G G, et al. Population pharmacokinetic and exposure-response safety analyses of mecbotamab vedotin (BA3011) in patients with advanced solid tumors[J]. 2023.

[2]. Mecbotamab. IMGT/mAb-DB.

 Chemical & Physical Properties

No Any Chemical & Physical Properties
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