Mecbotamab

Names

[ CAS No. ]:
2460400-28-4

[ Name ]:
Mecbotamab

Biological Activity

[Description]:

Mecbotamab is a humanized IgG1-κ antibody targeting to AXL receptor tyrosine kinase (AXL). Mecbotamab can serves as a conditionally active biologic (CAB), which can be conjugated with MMAE (HY-15162) via a cleavable linker, to form ADC Mecbotamab vedotin (BA3011)[1][2].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Protein Tyrosine Kinase/RTK >> TAM Receptor

[References]

[1]. Shen G G, et al. Population pharmacokinetic and exposure-response safety analyses of mecbotamab vedotin (BA3011) in patients with advanced solid tumors[J]. 2023.

[2]. Mecbotamab. IMGT/mAb-DB.

Chemical & Physical Properties

No Any Chemical & Physical Properties

Related Compounds

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