HIV-IN-5

Modify Date: 2025-09-05 11:27:47

HIV-IN-5 Structure
HIV-IN-5 structure
Common Name HIV-IN-5
CAS Number 2459929-62-3 Molecular Weight 572.59
Density N/A Boiling Point N/A
Molecular Formula C30H24N2O8S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of HIV-IN-5


HIV-IN-5 (compound 5r) is a potent HIV-1 inhibitor, with an IC50 of 0.16 μM. HIV-IN-5 shows inhibition of HIV DNA-dependent DNA polymerization activity, with an IC50 of 2.18 μM. HIV-IN-5 can bind to NNIBP (NNRTIs (non-nucleoside reverse transcriptase inhibitors) binding pocket) [1].

 Names

Name HIV-IN-5

 HIV-IN-5 Biological Activity

Description HIV-IN-5 (compound 5r) is a potent HIV-1 inhibitor, with an IC50 of 0.16 μM. HIV-IN-5 shows inhibition of HIV DNA-dependent DNA polymerization activity, with an IC50 of 2.18 μM. HIV-IN-5 can bind to NNIBP (NNRTIs (non-nucleoside reverse transcriptase inhibitors) binding pocket) [1].
Related Catalog
Target

HIV-1:0.16 ± 0.0 μM (IC50)

HIV-1 (Y181C):>100 μM (IC50)

HIV-1 (K103N):>100 μM (IC50)

References

[1]. Yi-MingLi, et al. Design, synthesis and anti-HIV evaluation of 5-alkyl- 6-(benzo[d][1,3]dioxol-5-alkyl)-2-mercaptopyrimidin-4(3H)-ones as potent HIV-1 NNRTIs. September 2020;102:104041.

 Chemical & Physical Properties

Molecular Formula C30H24N2O8S
Molecular Weight 572.59
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