1-(3-Aminophenyl)ethanol

Modify Date: 2024-01-03 06:22:07

1-(3-Aminophenyl)ethanol Structure
1-(3-Aminophenyl)ethanol structure
Common Name 1-(3-Aminophenyl)ethanol
CAS Number 2454-37-7 Molecular Weight 137.179
Density 1.1±0.1 g/cm3 Boiling Point 285.0±15.0 °C at 760 mmHg
Molecular Formula C8H11NO Melting Point 66-69 °C(lit.)
MSDS N/A Flash Point 126.1±20.4 °C

 Names

Name 1-(3-aminophenyl)ethanol
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 285.0±15.0 °C at 760 mmHg
Melting Point 66-69 °C(lit.)
Molecular Formula C8H11NO
Molecular Weight 137.179
Flash Point 126.1±20.4 °C
Exact Mass 137.084061
PSA 46.25000
LogP 0.10
Vapour Pressure 0.0±0.6 mmHg at 25°C
Index of Refraction 1.592

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DN5600000
CHEMICAL NAME :
Benzyl alcohol, m-amino-alpha-methyl-
CAS REGISTRY NUMBER :
2454-37-7
BEILSTEIN REFERENCE NO. :
2802415
LAST UPDATED :
199806
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C8-H11-N-O
MOLECULAR WEIGHT :
137.20
WISWESSER LINE NOTATION :
ZR CYQ1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
3100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU. Volume(issue)/page/year: 10,61,1954
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
3560 uL/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU. Volume(issue)/page/year: 10,61,1954

 Safety Information

Hazard Codes Xn: Harmful;
Risk Phrases R20/21/22
Safety Phrases S26-S37/39
WGK Germany 3
RTECS DN5600000

 Synthetic Route

~85%

1-(3-Aminophenyl)ethanol Structure

1-(3-Aminopheny...

CAS#:2454-37-7

Literature: JE IL PHARMACEUTICAL CO., LTD. Patent: US2011/218193 A1, 2011 ; Location in patent: Page/Page column 43 ; US 20110218193 A1

~94%

1-(3-Aminophenyl)ethanol Structure

1-(3-Aminopheny...

CAS#:2454-37-7

Literature: Zeynizadeh, Behzad; Ghasemi, Hamed Journal of Chemical Research, 2006 , # 8 p. 542 - 544

~%

1-(3-Aminophenyl)ethanol Structure

1-(3-Aminopheny...

CAS#:2454-37-7

Literature: Applied Catalysis A: General, , vol. 462-463, p. 121 - 128

~84%

1-(3-Aminophenyl)ethanol Structure

1-(3-Aminopheny...

CAS#:2454-37-7

Literature: Selvam, Parasuraman; Sonavane, Sachin U.; Mohapatra, Susanta K.; Jayaram, Radha V. Tetrahedron Letters, 2004 , vol. 45, # 15 p. 3071 - 3075

~%

1-(3-Aminophenyl)ethanol Structure

1-(3-Aminopheny...

CAS#:2454-37-7

Literature: Pharmaceutical Chemistry Journal, , vol. 32, # 11 p. 598 - 599 Khimiko-Farmatsevticheskii Zhurnal, , vol. 32, # 11 p. 31 - 32

~%

1-(3-Aminophenyl)ethanol Structure

1-(3-Aminopheny...

CAS#:2454-37-7

Literature: Biocatalysis and Biotransformation, , vol. 30, # 5-6 p. 469 - 475

~%

1-(3-Aminophenyl)ethanol Structure

1-(3-Aminopheny...

CAS#:2454-37-7

Literature: Journal of the American Chemical Society, , vol. 68, p. 185

 Synonyms

(3-Aminophenyl)-1-ethanol
1-(3-Aminophenyl)ethanol
EINECS 219-525-3
3-(1-Hydroxyethyl)aniline
MFCD00007798
m-Amino-α-methylbenzyl alcohol
Benzenemethanol, 3-amino-α-methyl-
Benzyl alcohol, m-amino-α-methyl-
(RS)-3-(1-hydroxyethyl)aniline
3-Amino-α-methylbenzyl alcohol
3-(α-Hydroxyethyl)-aniline
(m-Aminophenyl)methyl carbinol
m-(1-Hydroxyethyl)aniline