KTX-582 intermediate-2

Modify Date: 2024-01-25 09:18:57

KTX-582 intermediate-2 Structure
KTX-582 intermediate-2 structure
Common Name KTX-582 intermediate-2
CAS Number 2434850-07-2 Molecular Weight 495.37
Density N/A Boiling Point N/A
Molecular Formula C21H27BrN4O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of KTX-582 intermediate-2


KTX-582 intermediate-2 is an intermediate in the synthesis of KTX-582 (HY-148274) and can be used for ADC preparation. KTX-582 is an IRAK4 degrader and inducer of apoptosis with DC50 of 4 nM and 5 nM for IRAK4 and Ikaros, respectively[1].

 Names

Name KTX-582 intermediate-2

 KTX-582 intermediate-2 Biological Activity

Description KTX-582 intermediate-2 is an intermediate in the synthesis of KTX-582 (HY-148274) and can be used for ADC preparation. KTX-582 is an IRAK4 degrader and inducer of apoptosis with DC50 of 4 nM and 5 nM for IRAK4 and Ikaros, respectively[1].
Related Catalog
References

[1]. Mainolfi, et al. Preparation of heterocycles as IRAK degraders and uses thereof. World Intellectual Property Organization, WO2022147465 A1. 2022-07-07.

 Chemical & Physical Properties

Molecular Formula C21H27BrN4O5
Molecular Weight 495.37
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