KTX-582 intermediate-2

Names

[ CAS No. ]:
2434850-07-2

[ Name ]:
KTX-582 intermediate-2

Biological Activity

[Description]:

KTX-582 intermediate-2 is an intermediate in the synthesis of KTX-582 (HY-148274) and can be used for ADC preparation. KTX-582 is an IRAK4 degrader and inducer of apoptosis with DC50 of 4 nM and 5 nM for IRAK4 and Ikaros, respectively[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[References]

[1]. Mainolfi, et al. Preparation of heterocycles as IRAK degraders and uses thereof. World Intellectual Property Organization, WO2022147465 A1. 2022-07-07.

Chemical & Physical Properties

[ Molecular Formula ]:
C21H27BrN4O5

[ Molecular Weight ]:
495.37

Related Compounds

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