IHCH-3064

Modify Date: 2025-09-16 18:11:25

IHCH-3064 Structure
IHCH-3064 structure
Common Name IHCH-3064
CAS Number 2420562-65-6 Molecular Weight 479.49
Density N/A Boiling Point N/A
Molecular Formula C25H21N9O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of IHCH-3064


IHCH-3064 is a dual-acting compounds targeting Adenosine A2A Receptor and HDAC. IHCH-3064 exhibits potent binding to A2AR (Ki=2.2 nM) and selective inhibition of HDAC1 (IC50=80.2 nM), with good antiproliferative activity against tumor cell lines in vitro. IHCH-3064 is a tumor immunotherapeutic agent[1].

 Names

Name IHCH-3064

 IHCH-3064 Biological Activity

Description IHCH-3064 is a dual-acting compounds targeting Adenosine A2A Receptor and HDAC. IHCH-3064 exhibits potent binding to A2AR (Ki=2.2 nM) and selective inhibition of HDAC1 (IC50=80.2 nM), with good antiproliferative activity against tumor cell lines in vitro. IHCH-3064 is a tumor immunotherapeutic agent[1].
Related Catalog
References

[1]. Wenzhong Yan, et al. Structure-Based Design of Dual-Acting Compounds Targeting Adenosine A 2A Receptor and Histone Deacetylase as Novel Tumor Immunotherapeutic Agents. J Med Chem. 2021 Nov 25;64(22):16573-16597.

 Chemical & Physical Properties

Molecular Formula C25H21N9O2
Molecular Weight 479.49
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