MMP-2/9-IN-1

Modify Date: 2025-08-27 19:54:02

MMP-2/9-IN-1 Structure
MMP-2/9-IN-1 structure
Common Name MMP-2/9-IN-1
CAS Number 2415311-84-9 Molecular Weight 441.29
Density N/A Boiling Point N/A
Molecular Formula C14H16IN7S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of MMP-2/9-IN-1


MMP-2/9-IN-1 (Compound 4a) is a potent dual MMP-2 and MMP-9 inhibitor with IC50 values of 56 nM and 38 nM, respectively. MMP-2/9-IN-1 inhibits tumor growth, strongly induces cancer cell apoptosis, inhibits cell migration, and suppresses cell cycle progression leading to DNA fragmentation[1].

 Names

Name MMP-2/9-IN-1

 MMP-2/9-IN-1 Biological Activity

Description MMP-2/9-IN-1 (Compound 4a) is a potent dual MMP-2 and MMP-9 inhibitor with IC50 values of 56 nM and 38 nM, respectively. MMP-2/9-IN-1 inhibits tumor growth, strongly induces cancer cell apoptosis, inhibits cell migration, and suppresses cell cycle progression leading to DNA fragmentation[1].
Related Catalog
Target

MMP-2:56 nM (IC50)

MMP-9:38 nM (IC50)

References

[1]. Omar AM, et al. Novel molecular discovery of promising amidine-based thiazole analogues as potent dual Matrix Metalloproteinase-2 and 9 inhibitors: Anticancer activity data with prominent cell cycle arrest and DNA fragmentation analysis effects. Bioorg Chem. 2020 Aug;101:103992.

 Chemical & Physical Properties

Molecular Formula C14H16IN7S
Molecular Weight 441.29
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