ADTL-EI1712
Modify Date: 2024-04-18 12:05:02
ADTL-EI1712 structure
|
Common Name | ADTL-EI1712 | ||
|---|---|---|---|---|
| CAS Number | 2414916-45-1 | Molecular Weight | 505.440 | |
| Density | 1.6±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C22H18Cl2N4O2S2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of ADTL-EI1712ADTL-EI1712 is a potent, orally active, and selective dual-target inhibitor of ERK1 and ERK5, inhibition rates of ERK1/5 at 1 μM are 93.54% and 89.35%, respectively. ADTL-EI1712 can induce regulated cell death, a form of cell death that relies on the activation of genetically encoded machinery, to overcome compensatory mechanism in specific cancer cells in vitro and in vivo[1]. |
| Name | ADTL-EI1712 |
|---|---|
| Synonym | More Synonyms |
| Description | ADTL-EI1712 is a potent, orally active, and selective dual-target inhibitor of ERK1 and ERK5, inhibition rates of ERK1/5 at 1 μM are 93.54% and 89.35%, respectively. ADTL-EI1712 can induce regulated cell death, a form of cell death that relies on the activation of genetically encoded machinery, to overcome compensatory mechanism in specific cancer cells in vitro and in vivo[1]. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Molecular Formula | C22H18Cl2N4O2S2 |
| Molecular Weight | 505.440 |
| Exact Mass | 504.024811 |
| LogP | 4.08 |
| Index of Refraction | 1.768 |
| 2-[(2-Chlorobenzoyl)amino]-6-[(2-chlorophenyl)carbamothioyl]-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxamide |
| Thieno[2,3-c]pyridine-3-carboxamide, 2-[(2-chlorobenzoyl)amino]-6-[[(2-chlorophenyl)amino]thioxomethyl]-4,5,6,7-tetrahydro- |
| ADTL-EI1712 |