RET-IN-21

Modify Date: 2025-11-27 16:12:29

RET-IN-21 Structure
RET-IN-21 structure
 Common Name RET-IN-21
CAS Number 2414373-42-3 Molecular Weight 344.370
Density 1.4±0.1 g/cm3 Boiling Point N/A
Molecular Formula C19H16N6O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of RET-IN-21


RET-IN-21 is an inhibitor of receptor tyrosine kinase (RET), with the IC50 of 4.4 μM, that has antitumor activity[1].

 Names

Name 4-{5-[(4-Pyridinylmethyl)amino]pyrazolo[1,5-a]pyrimidin-3-yl}benzamide
Synonym More Synonyms

 RET-IN-21 Biological Activity

Description RET-IN-21 is an inhibitor of receptor tyrosine kinase (RET), with the IC50 of 4.4 μM, that has antitumor activity[1].
Related Catalog
References

[1]. Rebecca Newton, et al. Discovery and Optimization of wt-RET/KDR-Selective Inhibitors of RETV804M Kinase. ACS Med. Chem. Lett. 2020, 11, 4, 497–505

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Molecular Formula C19H16N6O
Molecular Weight 344.370
Exact Mass 344.138550
LogP -0.72
Index of Refraction 1.729

 Synonyms

Benzamide, 4-[5-[(4-pyridinylmethyl)amino]pyrazolo[1,5-a]pyrimidin-3-yl]-
4-{5-[(4-Pyridinylmethyl)amino]pyrazolo[1,5-a]pyrimidin-3-yl}benzamide
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.
Top Suppliers:I want be here

Get all suppliers and price by the below link:

RET-IN-21 suppliers

RET-IN-21 price

Related Compounds: More...
1,4-Bis(4,7-dimethoxybenzo[d]thiazol-2-yl)piperazine
863001-49-4
2-(3-(4-fluorobenzyl)-7-oxo-3H-[1,2,3]triazolo[4,5-d]pyrimidin-6(7H)-yl)-N-(4-(trifluoromethoxy)phenyl)acetamide
892472-57-0
2-{3-[(2-fluorophenyl)methyl]-7-oxo-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-6-yl}-N-[4-(trifluoromethoxy)phenyl]acetamide
892473-66-4
6-(2-(4-benzylpiperidin-1-yl)-2-oxoethyl)-3-(4-fluorophenyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7(6H)-one
863019-51-6
2-(3-(4-fluorophenyl)-7-oxo-3H-[1,2,3]triazolo[4,5-d]pyrimidin-6(7H)-yl)-N-(3-(trifluoromethyl)phenyl)acetamide
892480-43-2
2-(3-(4-fluorophenyl)-7-oxo-3H-[1,2,3]triazolo[4,5-d]pyrimidin-6(7H)-yl)-N-(4-(trifluoromethyl)phenyl)acetamide
892480-45-4
6-(2-(4-benzylpiperidin-1-yl)-2-oxoethyl)-3-(3-chlorophenyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7(6H)-one
863019-65-2
N-(2-chloro-5-(trifluoromethyl)phenyl)-2-(3-(4-methoxyphenyl)-7-oxo-3H-[1,2,3]triazolo[4,5-d]pyrimidin-6(7H)-yl)acetamide
863019-88-9
N-(2-chloro-5-(trifluoromethyl)phenyl)-2-(3-(4-ethoxyphenyl)-7-oxo-3H-[1,2,3]triazolo[4,5-d]pyrimidin-6(7H)-yl)acetamide
863019-95-8
2-(3-(4-ethoxyphenyl)-7-oxo-3H-[1,2,3]triazolo[4,5-d]pyrimidin-6(7H)-yl)-N-(4-(trifluoromethoxy)phenyl)acetamide
896677-99-9
Chemsrc provides RET-IN-21(CAS#:2414373-42-3) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of RET-IN-21 are included as well.>> amp version: RET-IN-21

Home | MSDS/SDS Database Search | Journals | Product Classification | Biologically Active Compounds | Selling Leads | About Us | Disclaimer

Copyright © 2024 ChemSrc All Rights Reserved