ZXH-1-161

Modify Date: 2024-01-14 16:31:25

ZXH-1-161 structure	Common Name	ZXH-1-161
	CAS Number	2407654-51-5	Molecular Weight	468.51
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₆H₂₄N₆O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of ZXH-1-161

ZXH-1-161 is a potent cereblon (CRBN) modulator with an IC50 value of 39 nM in MM1.S wild type cells. ZXH-1-161 has selective degradation activity towards GSPT1. ZXH-1-161 can be used for researching multiple myeloma[1].

Name	ZXH-1-161

Description	ZXH-1-161 is a potent cereblon (CRBN) modulator with an IC50 value of 39 nM in MM1.S wild type cells. ZXH-1-161 has selective degradation activity towards GSPT1. ZXH-1-161 can be used for researching multiple myeloma[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> Ligand for E3 Ligase
Target	IC50: 39 μM in MM1.S wild type cells[1]
References	[1]. Powell CE, et al. Selective Degradation of GSPT1 by Cereblon Modulators Identified via a Focused Combinatorial Library. ACS Chem Biol. 2020 Oct 16;15(10):2722-2730.

Molecular Formula	C₂₆H₂₄N₆O₃
Molecular Weight	468.51

ZXH-1-161

Use of ZXH-1-161

Names

ZXH-1-161 Biological Activity

Chemical & Physical Properties