Zxh-1-161

Modify Date: 2024-01-14 16:31:25

Zxh-1-161 Structure
Zxh-1-161 structure
Common Name Zxh-1-161
CAS Number 2407654-51-5 Molecular Weight 468.51
Density N/A Boiling Point N/A
Molecular Formula C26H24N6O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Zxh-1-161


ZXH-1-161 is a potent cereblon (CRBN) modulator with an IC50 value of 39 nM in MM1.S wild type cells. ZXH-1-161 has selective degradation activity towards GSPT1. ZXH-1-161 can be used for researching multiple myeloma[1].

 Names

Name ZXH-1-161

 Zxh-1-161 Biological Activity

Description ZXH-1-161 is a potent cereblon (CRBN) modulator with an IC50 value of 39 nM in MM1.S wild type cells. ZXH-1-161 has selective degradation activity towards GSPT1. ZXH-1-161 can be used for researching multiple myeloma[1].
Related Catalog
Target

IC50: 39 μM in MM1.S wild type cells[1]

References

[1]. Powell CE, et al. Selective Degradation of GSPT1 by Cereblon Modulators Identified via a Focused Combinatorial Library. ACS Chem Biol. 2020 Oct 16;15(10):2722-2730.

 Chemical & Physical Properties

Molecular Formula C26H24N6O3
Molecular Weight 468.51
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