HIF-IN-1

Modify Date: 2025-08-24 16:44:44

HIF-IN-1 Structure
HIF-IN-1 structure
Common Name HIF-IN-1
CAS Number 2393928-76-0 Molecular Weight 260.29
Density N/A Boiling Point N/A
Molecular Formula C17H12N2O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of HIF-IN-1


HIF-IN-1 (Compound 3c) is a hypoxia-inducible factor (HIF)-1 inhibitor. HIF-IN-1 suppresses HIF-1α protein accumulation without affecting the levels of HIF-1α mRNA. HIF-IN-1 shows no obvious cytotoxicity[1].

 Names

Name HIF-IN-1

 HIF-IN-1 Biological Activity

Description HIF-IN-1 (Compound 3c) is a hypoxia-inducible factor (HIF)-1 inhibitor. HIF-IN-1 suppresses HIF-1α protein accumulation without affecting the levels of HIF-1α mRNA. HIF-IN-1 shows no obvious cytotoxicity[1].
Related Catalog
References

[1]. Fuse S, et al. Design, synthesis, and evaluation of indeno[2,1-c]pyrazolones for use as inhibitors against hypoxia-inducible factor (HIF)-1 transcriptional activity. Bioorg Med Chem. 2020 Jan 1;28(1):115207.

 Chemical & Physical Properties

Molecular Formula C17H12N2O
Molecular Weight 260.29
InChIKey ZMPVOQJDQIWRJZ-UHFFFAOYSA-N
SMILES Cc1ccc(-n2ncc3c2C(=O)c2ccccc2-3)cc1
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