Cholestenone-d7

Modify Date: 2024-01-05 17:43:58

Cholestenone-d7 structure	Common Name	Cholestenone-d7
	CAS Number	2389048-48-8	Molecular Weight	391.68
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₇H₃₇D₇O	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Cholestenone-d7

Cholestenone-d7 is deuterium labeled Cholestenone. Cholestenone (4-Cholesten-3-one), the intermediate oxidation product of cholesterol, is metabolized primarily in the liver. Cholestenone is highly mobile in membranes and influences cholesterol flip-flop

Name	Cholestenone-d7

Description	Cholestenone-d7 is deuterium labeled Cholestenone. Cholestenone (4-Cholesten-3-one), the intermediate oxidation product of cholesterol, is metabolized primarily in the liver. Cholestenone is highly mobile in membranes and influences cholesterol flip-flop
Related Catalog	Research Areas >> Metabolic Disease
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[3].
References	[1]. Rosenheim O, et al. The mechanism of coprosterol formation in vivo: 1. Cholestenone as an intermediate. Biochem J. 1943 Oct;37(4):513-4. [2]. Neuvonen M, et, al. Enzymatic oxidation of cholesterol: properties and functional effects of cholestenone in cell membranes. PLoS One. 2014 Aug 26;9(8):e103743. [3]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223.

Molecular Formula	C₂₇H₃₇D₇O
Molecular Weight	391.68

Cholestenone-d7

Use of Cholestenone-d7

Names

Cholestenone-d7 Biological Activity

Chemical & Physical Properties